The effect of topical tranexamic acid injection on bleeding during and after tonsillectomy in patients aged 15 to 45 years

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20211028052900N2

Enrollment

Registered

2022-05-01

Start date

2022-04-03

Completion date

Unknown

Last updated

2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

TONSILECTOMY.

Interventions

Intervention 1: Intervention group: 10 minutes before surgery, 100 mg of tranexamic acid is injected randomly into the bed of the right or left tonsil. The amount of intraoperative bleeding is calcula

Eligibility

Sex/Gender

All

Age

15 Years to 45 Years

Inclusion criteria

Inclusion criteria: 15 to 45 years old Functional class 1 and 2

Exclusion criteria

Exclusion criteria: contraindication of the use of tranexamic acid for any reason, including allergies to the drug Anticoagulants consumption Hematologic disorders Uncontrolled systemic diseases Use a catheter to control bleeding during surgery

Design outcomes

Primary

Measure	Time frame
Amount of bleeding during tonsillectomy. Timepoint: 24 hour after surgery. Method of measurement: The amount of blood collected in the suction and the change in weight of the soaked gas.	—

Secondary

Measure	Time frame
Surgeon satisfaction. Timepoint: after surgery. Method of measurement: Scale one to ten.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactali badrooj

Esfahan University of Medical Sciences

abadrooj@gmail.com+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026