The effects of probiotics administration on acute side effects of chemotherapy regimens in gastroesophageal cancer patients

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20211024052857N1

Enrollment

Registered

2021-11-08

Start date

2021-11-26

Completion date

Unknown

Last updated

2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastroesophageal cancers.

Interventions

Intervention 1: Intervention group: Patients will be given probiotics (" DailyEast", Zist Takhmir ) once a daily during their chemotherapy. Intervention 2: Control group: Patients will be given their

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with gastroesophageal cancer stage 3,4 who had chemotherapy(dcf,folfox)-induced side effects and were older than 18 with first-grade tumor.

Exclusion criteria

Exclusion criteria: Patients with severe systematic disease (such as heart, kidney, and liver) or previously had chemotherapy or were given antibiotics and probiotics.

Design outcomes

Primary

Measure	Time frame
Evaluation of side effects of chemotherapy in patients with gastroesophageal cancers. Timepoint: Duration of chemotherapy. Method of measurement: Standard questionnaire based CTCAE.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Tojjari

Karaj University of Medical Sciences

alirezatojjari@gmail.com+98 21 2257 1179

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026