Open Fractures in Limbs. Injury of unspecified body region
Conditions
Interventions
Intervention 1: In the intervention group, after primary skin prep with betadine 7%, for secondary prep, 10% betadine solution with vancomycin powder in the amount of 2 g is used and it will be done u
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Diagnosis of open fracture and the need for open reduction and internal fixation surgery The patient should not be referred to the operating room as a vital emergency and should be fasted for 8 hours before the operation Age between 18 and 65 years Having a body mass index between 18 and 25 Not pregnant during the study Lack of sensitivity to seafood No autoimmune diseases and immune system defects (Guillain-Barre, multiple sclerosis, immune deficiency syndrome, etc.) Not having any declining bone disease Do not take antibiotics one week before surgery No skin diseases No history of orthopedic and neurosurgery during the last 6 months Absence of cIII degree open fractures in Gastillo Anderson classification No smoking and drug addiction Lack of underlying and autoimmune diseases (diabetes, multiple sclerosis, immune deficiency syndrome, etc.) No previous allergy to antibiotics and disinfectants Informed consent
Exclusion criteria
Exclusion criteria: Intraoperative blood transfusion Unforeseen events before surgery such as cardiac arrest and death Patient death during study (within 30 days after surgery) Bleeding more than 200 cc Duration of surgery more than 2 hours Arbitrary use of antibiotics without a doctor's prescription The interval between going to the emergency room and surgery is more than 23 hours Reluctance to continue participating in research
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Infection. Timepoint: The first, second, fourteenth and twenty-eighth days after surgery. Method of measurement: Visual scale analog and laboratory sampling. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactYaser Abolhasani Heydarabad
Esfahan University of Medical Sciences
Outcome results
None listed