Sedation before Intubation.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with American society of anesthesiologist (ASA) class 3 and 4 who are admitted in ICU of poisoned patients Age between 18 to 80 Patients whom are going to be intubated Not taking sedative drugs before admitting to intensive care unit (ICU)
Exclusion criteria
Exclusion criteria: known allergy to any of the drugs used in this study advanced liver disease Serum creatinine level above 200 micromol/liter Unstable angina or acute myocardial infarction patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amount of sedation caused by drug according to RASS scale. Timepoint: Before intervention and then every 2 hours. Method of measurement: RASS scale system is a known scale in the world that measured the rate of sedation whom admitted to ICU. Scoring points in this scale include -5 to +4 that the +4 point belongs to agitated and aggressive patients who are a threat for ICU personals. the -5 points belongs to the patients who are not responding to voice and physical stimulations and they are not conscious. the rest of points are spectrum between these two scores.;Blood pressure in the admitted patients of ICU. Timepoint: Before intervention and then every 2 hours. Method of measurement: Vital sign monitoring device.;Heart rate. Timepoint: Before intervention and then every 2 hours. Method of measurement: Vital sign monitoring device. | — |
Countries
Iran (Islamic Republic of)
Contacts
Esfahan University of Medical Sciences