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Comparison the amoxicillin and pantoprazole regimen with quadruple regimen for Helicobacter pylori eradication

Comparison of the efficacy of the amoxicillin and pantoprazole regimen with clarithromycin-based quadruple regimen for Helicobacter pylori eradication

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211019052812N1
Enrollment
166
Registered
2021-11-06
Start date
2021-11-22
Completion date
Unknown
Last updated
2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori infection. Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere

Interventions

Intervention 1: Intervention group: (dual regimen): amoxicillin 1000 mg every 12 hours (Farabi pharmaceutical CO., Iran) and pantoprazole 40 mg every 12 hours (Tehranchemie CO., Iran) for 14 days and

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age more than 18 years Confirm diagnosis of H. pylori infection by stool antigen test No previous treatment of H. pylori infection Patient consent to participate in the study

Exclusion criteria

Exclusion criteria: Use of antibiotics or nonsteroidal anti-inflammatory drugs (NSAIDs) in the last 4 weeks allergy to any of the studied drugs History of gastric surgery or the presence of a serious concomitant disease such as cancer, Pregnant or lactating women

Design outcomes

Primary

MeasureTime frame
Presence of Helicobacter pylori infection. Timepoint: Two weeks after the end of treatment. Method of measurement: Assess the presence of infection based on Stool Antigen Test.

Secondary

MeasureTime frame
Treatment complication. Timepoint: Patients clinical visits every two weeks and fallow up by phone call every week. Method of measurement: Presence of nausea, vomiting and any allergic reactions based on clinical information.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamira Mohammadi

Ahvaz University of Medical Sciences

mohammadi.s@ajums.ac.ir+98 61 3001 3374

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026