dystonia. Dystonia
Conditions
Interventions
Intervention 1: Intervention group:Liposomal cannabidiol drops are given at a dose of 10 mg every 6 hours. The drug is started with a dose of 10 mg every 12 hours (2 ml) and after 5 days is increased
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with focal-generalized dystonia Failure to improve the patient's dystonic symptoms with previous drug treatments
Exclusion criteria
Exclusion criteria: Evidence that dystonia is secondary to other diseases History of liver disease Pregnancy or intent to conceive or breastfeed History of dystonic surgery, including deep brain stimulation and destructive surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intensity of dystonia motion symptoms based on Van Marsden Scale and Global Dystonia Scale and TWSTRS. Timepoint: Before the intervention (0), then 3, 6, and 9 weeks after the start of the intervention or placebo. Method of measurement: Van Marsden Scale and Global Dystonia Scale and TWSTRS. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life using SF-36 questionnaire. Timepoint: Before the intervention (0), then 3, 6, and 9 weeks after the start of the intervention or placebo. Method of measurement: SF-36 questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactOlfati Nahid
Mashhad University of Medical Sciences
Outcome results
None listed