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Effect of Variable Doses of Metronidazole in Treatment of Helicobacterpylori

Comparison of Therapeutic Effects of Metronidazole in Variable Doses in Eradication of Helicobacterpylori in Dyspeptic Patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211012052740N1
Enrollment
170
Registered
2021-10-16
Start date
2021-12-06
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori Infection. Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere

Interventions

Intervention 1: Intervention group: Group B Receives Following Medications for 14 Days: Tab Metronidazole 500 mg TDS, Omeprazole 20 mg BID, Amoxicillin 1000 mg BID, Bismuth Subcitrate 135 mg BID. Int

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Dyspeptic Patients with Positive Helicobacterpylori Stool Antigen Test Older than 18 Years Old Persons

Exclusion criteria

Exclusion criteria: No Referring After Taking the Medication Taking Medications for Less than 10 Days Pregnant or Breastfeeding Women Patients with the History of Major Cardiac, Pulmonary, Renal or Hepatic Disease History of Known Side Effects to the Medications of Therapeutic Regimen Taking Antibiotic during the Last Month

Design outcomes

Primary

MeasureTime frame
Eradication of Helicobacter pylori Infection. Timepoint: Four Weeks after the Termination of Treatment. Method of measurement: Helicobacter pylori Stool Antigen Test.

Secondary

MeasureTime frame
Drug Adverse Effects Including: Nausa, Abdominal Pain, Metallic Taste, Diarrhea. Timepoint: Four Weeks after Starting the Treatment. Method of measurement: Questionnaire.;The Tolerance to Accepting the Treatment (Taking Medications more than 10 Days). Timepoint: Two Weeks after Starting the Treatment. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadreza Mohammad Hoseiny Azar

Oroumia University of Medical Sciences

mohammadazar@gmail.com+98 44 3346 2420

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026