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The effect of intranasal ketamine on pain intensity after cesarean section

The effect of intranasal ketamine on pain intensity after cesarean section

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211011052726N1
Enrollment
120
Registered
2021-11-08
Start date
2020-10-22
Completion date
Unknown
Last updated
2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe postpartum pain. Encounter for full-term uncomplicated delivery

Interventions

Intervention 1: Intervention group: One 4 mg tizanidine tablet (made by Galenus) is taken orally one hour before the operation and one tablet 24 hours later. Intervention 2: Control group: A dose of 0

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: Candidate for non-emergency cesarean section Age between 20-35

Exclusion criteria

Exclusion criteria: The patient's unwillingness to continue participating in the study at any time Prolongation of cesarean section (more than 1.5 hours) Increased incision length for any reason Occurrence of any unusual complication during surgery Unstable vital signs History of cardiovascular disease and hypertension History of mental disorders Known allergy to ketamine History of drug addiction

Design outcomes

Primary

MeasureTime frame
Intensity of pain. Timepoint: Enter recovery 15, 30, 60 minutes and 2, 6, 12 hours after surgery. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
Nausea and vomiting. Timepoint: Enter recovery 15, 30, 60 minutes and 2, 6, 12 hours after surgery. Method of measurement: Question from the patient (questionnaire).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNafiseh Faghani Makrani

Mazandaran University of Medical Sciences

dr.nfaghani@gmail.com+98 11 3336 1700

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026