Evaluation of the effect of different microbotox methods in the treatment of open pores

Comparison of the effect of botulinum toxin A injection by microneedling with intradermal injection by syringe in the treatment of patients with open pores

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20211010052723N2

Enrollment

Registered

2022-07-01

Start date

2022-07-23

Completion date

Unknown

Last updated

2022-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dilated pores.

Interventions

Intervention 1: Intervention group:Using local anesthesia at the treatment site, which remains on the site for half an hour, then the site is washed with normal saline and sterilized using aseptic sol

Eligibility

Sex/Gender

All

Age

25 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patient consent to participate in the study Age over 25 years No history of allergic reaction to botulinum toxin

Exclusion criteria

Exclusion criteria: Taking topical retinoids or oral isotretinoin in the last three months Laser or chemical peels during the last 6 months Myasthenia Gravis Pregnant and lactating women

Design outcomes

Primary

Measure	Time frame
Dermoscopic changes. Timepoint: Before and one month after. Method of measurement: Dermoscopy (number of pores and their size in a specific area) by examining shallow holes, holes filled with keratotic plugs and yellow spots.;Likert satisfaction. Timepoint: One month after work. Method of measurement: Also, one month after treatment, the Likert satisfaction criterion (1-5 scale) will be used to assess patient satisfaction. (11)1 = Very dissatisfied2 = Dissatisfied3 = Neither satisfied nor dissatisfied4 = Satisfied5 = Very satisfied.;The Quartile improvement scale. Timepoint: One month after doing. Method of measurement: Photographs will be taken before and one month after treatment and the pore size improvement will be evaluated by two dermatologists who are blind to the study with the Quartile improvement scale (0-4 scale) as follows (11). ) 0 = No improvement1 = Minor / mild improvement (1% -25%) 2 = Moderate improvement (26% -50%) 3 = Marked improvement (51% -75%) 4 = Very significant improvement (76% -100% ).	—

Measure

Time frame

Dermoscopic changes. Timepoint: Before and one month after. Method of measurement: Dermoscopy (number of pores and their size in a specific area) by examining shallow holes, holes filled with keratotic plugs and yellow spots.;Likert satisfaction. Timepoint: One month after work. Method of measurement: Also, one month after treatment, the Likert satisfaction criterion (1-5 scale) will be used to assess patient satisfaction. (11)1 = Very dissatisfied2 = Dissatisfied3 = Neither satisfied nor dissatisfied4 = Satisfied5 = Very satisfied.;The Quartile improvement scale. Timepoint: One month after doing. Method of measurement: Photographs will be taken before and one month after treatment and the pore size improvement will be evaluated by two dermatologists who are blind to the study with the Quartile improvement scale (0-4 scale) as follows (11). ) 0 = No improvement1 = Minor / mild improvement (1% -25%) 2 = Moderate improvement (26% -50%) 3 = Marked improvement (51% -75%) 4 = Very significant improvement (76% -100% ).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahya Abedini

Esfahan University of Medical Sciences

Aabedini.ma@gmail.com+98 31 3621 8308

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026