Investigating the effect of autologous platelet factor in ear repair

Investigating the effect of using autologous platelet factor in accelerating mastoidectomy repair with removal of the posterior wall and comparing it with the control group.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20211010052721N3

Enrollment

Registered

2022-10-22

Start date

2020-11-21

Completion date

Unknown

Last updated

2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mastoidectomy. Other disorders of ear and mastoid process following mastoidectomy

Interventions

Intervention 1: Intervention group: In this group of patients, in addition to Gelfoam, from 4 to 8 cc of throat fibrin enriched with platelets (Iranian Blood Transfusion Organization, Mashhad, Iran) w

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient satisfaction Performing mastoidectomy by removing the posterior wall

Exclusion criteria

Exclusion criteria: Having anemia Complications during surgery such as facial paralysis Breastfeeding Pregnancy

Design outcomes

Primary

Measure	Time frame
The duration of epithelialization of the eardrum. Timepoint: At the beginning of the study (before the start of the intervention) and 14, 30 and 90 days after the use of autologous platelet factor. Method of measurement: Otoscopy with a microscope.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNavid Nourizadeh

Mashhad University of Medical Sciences

Nourizadehn@mums.ac.ir009838451521

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026