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Evaluation of the effect of nebulized heparin on days without ventilator in intensive care unit patients

Evaluation of the effect of nebulized heparin on days without ventilator in intensive care unit patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20211010052718N2
Enrollment
74
Registered
2022-05-19
Start date
2022-04-19
Completion date
Unknown
Last updated
2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute respiratory distress syndrom. Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapors

Interventions

Intervention 1: Intervention group:Heparin ???? international unit 1 ml(Caspian Supply, Tehran, Iran)Will be prescribedPatients for 7 days heparin nebulizer at a dose of 5000 unitsThey will receive it

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients of both sexes and over 18 years old They needed more than 2 hours of aggressive mechanical ventilation GCS above 9 No underlying pulmonary problems

Exclusion criteria

Exclusion criteria: Patients receiving therapeutic doses of heparin enoxaparin, warfarin or dabigatran during the study Uncontrolled bleeding or a history of bleeding such as cerebral hemorrhage in the past year and patients who had an epidural catheter or were implanted within 2 hours of hospitalization. Patients with heparin sensitivity

Design outcomes

Primary

MeasureTime frame
Improve oxygenation. Timepoint: After starting the intervention on a daily basis for 15 days. Method of measurement: Arterial blood sampling device.

Secondary

MeasureTime frame
Compliance. Timepoint: After starting the intervention on a daily basis for 15 days. Method of measurement: Ventilator.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Nikzad

Mazandaran University of Medical Sciences

A.NIKZAD@MAZUMS.AC+98 11 3336 1700

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026