LIVER TRANSPLANT. Surgical operation with transplant of whole organ as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
Conditions
Interventions
Intervention 1: Intervention group: blood transfusion from a brain dead donor to a patient undergoing liver transplantation.The outcome of patients after transplantation is checked and recorded based
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Stability in vital signs (heart rate less than 100 R/M, systolic pressure more than 100 mmHg). Hemoglobin level above 11 Age 18 to 40 years having blood group and RH between the donor and the recipient The same immunological conditions between donor and recipient in terms of cytomegaloviruses Matching based on sender and receiver cross match Transplantation from a brain dead donor Whole liver transplant Stability of vital signs at the time of liver transplant surgery Failure to receive inotrope before the transplant procedure No grade 3 or 4 encephalopathy before transplantation Age between 18 and 40 years Absence of evidence of portal vein thrombosis in preoperative examinations Liver transplant for the first time Not having a history of hepatic vein thrombosis (Bodekiari syndrome) or other diseases with high blood coagulation potential.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding rate during liver transplant surgery and after surgery (first 24 hours). Timepoint: During the operation and up to 24 hours after the operation. Method of measurement: Questionnaire.;The amount of blood injected during the liver transplant operation and after the operation (first 24 hours). Timepoint: During the operation and up to 24 hours after the operation. Method of measurement: Questionnaire.;The rate of hepatic artery thrombosis during liver transplantation and after the operation (the first two weeks after transplantation). Timepoint: During the transplant operation up to two weeks after the transplant. Method of measurement: Doppler ultrasound, CT abdominal angiography.;Mortality rate during liver transplant surgery and after surgery (first 30 days after transplant). Timepoint: The first 30 days after liver transplantation. Method of measurement: questionnaire.;The degree of initial dysfunction of the transplanted liver (during the first week). Number of days of hospitalization in ICU after transplantation. Timepoint: The first week after transplantation. Method of measurement: questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactalireza shamsaefar
Shiraz University of Medical Sciences
Outcome results
None listed