Prostate Cancer.
Conditions
Interventions
Intervention 1: Control group: This group undergoes external radiotherapy. Before the start of treatment and after one month and three months after the end of external radiotherapy, the level of infla
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age =18 year Eastern Cooperative Oncology Group (ECOG) performance zero or one Localized prostate adenocarcinoma confirmed by pathology with moderate (Unfavorable) and high risk according to National Comprehensive Cancer Network criteria(NCCN) (first edition 2021)
Exclusion criteria
Exclusion criteria: Severe physical illness or mental disorder that, according to the researcher, prevents treatment according to the protocol Patients who cannot be followed up regularly Contraindications for external radiotherapy or brachytherapy Previous history of external radiotherapy or prostate brachytherapy History of any prostate surgery Any history of malignancy (except for non-melanoma skin cancers) History of Chemotherapy, Targeted Therapy and the use of immunosuppressive drugs History of chronic infectious diseases (HIV, viral hepatitis, etc.)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum profile of inflammatory cytokines. Timepoint: Serum levels of inflammatory cytokines are measured two weeks before the start of radiotherapy, and one and three months after the end of radiotherapy. Method of measurement: Blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli bagheri
Ahvaz University of Medical Sciences
Outcome results
None listed