Patients with hypertension with mild renal failer. Hypertensive chronic kidney disease
Conditions
Interventions
Intervention 1: In the first group, 25 mg of hydrochlorothiazide tablets and 40 mg of valsartan tablets daily every 12 hours for 3 months. Intervention 2: Control group: Control group: Group 2: 420 mg
Sponsors
Gorgan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Non-pregnant man or woman 18 to 70 years old 2. Consent to participate in the study 3. A patient with confirmed clinical signs of hypertension with mild renal failure 4. Abnormal blood pressure (=> 130/80 according to AHA criteria) 5. Patient follow-up
Exclusion criteria
Exclusion criteria: 1- Allergy to the plant 2- Normal blood pressure (mm HgSBP = 120; DBP = 80 mm Hg) / blood pressure below 100 and blood pressure => 160/100 3- Patients with diabetes mellitus, severe renal failure, coronary artery disease, heart failure, malignant hypertension [BP = 180/110], etc.) 4- Study of changing antihypertensive drugs in patients 5- Systolic blood pressure below 100 during the study 6- Pregnancy 7. Any metabolic or malabsorption disease that may interfere with the absorption of hibiscus (such as celiac disease, chronic pancreatitis, etc.). 8- Use of psychiatric drugs (mood stabilizer, anti-depressant, anti-anxiety or anti-psychotic
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patients' blood pressure changes,, albuminuria and proteinuria. Timepoint: Blood pressure at the beginning and 3 months after the intervention. Method of measurement: Based on laboratory Examination.;Electrolytes. Timepoint: Electrolytes at the beginning and 3 months after the start of the intervention. Method of measurement: Based on laboratory Examination.;Albuminuria and proteinuria. Timepoint: albuminuria, proteinuria, GFR according to MDRD formula. Method of measurement: Based on laboratory Examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBehdad Dehkhoda
Gorgan University of Medical Sciences
Outcome results
None listed