drug Resistant partial epilepsy. Localization-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localized onset, intractable
Conditions
Interventions
Intervention 1: The first intervention group is resistant partial onset epilepsy receiving lacosamide . Lacosamide is started orally at a dose of 50 mg twice daily and is increased to 300 mg daily dep
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with resistant partial onset epilepsy written informed consent age more than 18 years
Exclusion criteria
Exclusion criteria: cardiac arrhythmias for lacosamide group pregnancy for lacosamide group renal failure for levetiracetam group mood disorders for levetiracetam group
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of seizures in resistant partial onset epilepsy. Timepoint: Three months before the intervention, 1, 2 and 3 months after taking the drug. Method of measurement: questionnaire.;Abnormal changes in the electroencephalogram. Timepoint: before the intervention and 3 months after taking drugs. Method of measurement: taking electroencephalogram. | — |
Secondary
| Measure | Time frame |
|---|---|
| Drug side effects after taking lacosamide and levetiracetam. Timepoint: Within three months after starting the drug. Method of measurement: questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Maryam Sadat Hosseini Darenjani
Esfahan University of Medical Sciences
Outcome results
None listed