Investigating the effect of tranexamic acid on tonsillectomy

Investigating the effect of topical tranexamic acid in level of bleeding during and after tonsillectomy surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210923052559N3

Enrollment

Registered

2023-11-22

Start date

2023-12-10

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Haemorrhage due to tonsillectomy surgery. Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care

Interventions

Intervention 1: Intervention group: In this group, immediately at the beginning of the tonsillectomy procedure, trangesamic acid (a 5 ml vial of trangesmic acid 100 mg/ml) will be injected at the dose

Eligibility

Sex/Gender

All

Age

5 Years to 18 Years

Inclusion criteria

Inclusion criteria: Informed consent of the patient Patients who are candidates for tonsillectomy surgery

Exclusion criteria

Exclusion criteria: Suffering from bleeding diseases The presence of tonsillar hypertrophy History of sensitivity to tranexamic acid Abnormal bleeding from the adenoid during surgery Taking drugs that may increase bleeding, such as aspirin

Design outcomes

Primary

Measure	Time frame
The amount of bleeding. Timepoint: During surgery, 24 hours and one week after surgery. Method of measurement: The amount of bleeding is calculated based on the amount of suctioned blood and gas pack. The blood volume of each small gas of 10 x 10 cm size is considered to be about 12 cc, the blood volume in the suction tube is also evaluated.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactImaneh Roshanzamir

Mashhad University of Medical Sciences

roshanzamiri@mums.ac.ir+98 51 3801 2649

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026