Investigating the effect of botulinum toxin on parotidectomy

Evaluation the effectiveness of botulinum toxin injection in improving the complication of Sialocele after parotidectomy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210923052559N2

Enrollment

100

Registered

2023-02-06

Start date

2023-02-14

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neoplasm of parotid gland. Benign neoplasm of parotid gland

Interventions

Intervention 1: Intervention group: Patients of this group who have undergone partial parotidectomy surgery and during surgery a 500 cc vial is diluted with 2.5 cc of normal saline, each 0.5 cc of no

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Tumor located in the superficial parotid lobe Benign pathological results in preoperative fine needle aspiration Full consent to enter the study

Exclusion criteria

Exclusion criteria: Facial paralysis before surgery History of Botox in the last 3 months Allergy or allergic reaction to Botox Pregnancy Breastfeeding History of spastic cerebral palsy Suffering from all types of severe respiratory failure

Design outcomes

Primary

Measure	Time frame
Swelling of the fistula and sialocele. Timepoint: Before the start of the intervention and 48 hours after surgery and the use of botulinum toxin. Method of measurement: Sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKamran khazayeni

Mashhad University of Medical Sciences

khazaenik@mums.ac.ir+98 51 3801 2649

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026