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Assessment of the efficacy of amnion dressing in wound healing of skin graft donor sites

Assessment of the efficacy of amnion dressing in wound healing of skin graft donor sites (superficial second-degree wound) in the lateral thigh and its comparison with conventional wound dressing

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210918052511N1
Enrollment
58
Registered
2021-09-24
Start date
2021-10-22
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burn patients. Burn and corrosion of head, face, and neck

Interventions

Intervention 1: Intervention group: The amnion dressing is used for two weeks and this dressing is provided by Sinacell Co.Amnion membrane as a biological dressing in the treatment of burn wounds acce

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 55 Years

Inclusion criteria

Inclusion criteria: Patients between the ages of 15 and 55 are eligible to participate. Have a severe burn of grade 2 or higher that requires a skin graft Patients with burns that are less than or equal to 20% Patient with deep second degree burns in upper and lower limbs and anterior trunk except lateral thigh

Exclusion criteria

Exclusion criteria: Patients who are receiving chemotherapy Patients taking corticosteroids or cytotoxic medicines Pregnancy Cancer, cytotoxic drugs, immunosuppressants, and the presence of chronic diseases other than diabetes that affect wound healing, such as severe vascular disease, lupus, rheumatoid arthritis, and renal failure Smoking The presence of an underlying disease leads to a defective immune system Diabetic patients Taking drugs that lead to a defective immune system. Burns in the lateral thigh area.

Design outcomes

Primary

MeasureTime frame
Duration of complete wound healing. Timepoint: Every 48 hours. Method of measurement: Based on the clinical observations of an infectious disease specialist and plastic and burn surgeon.

Secondary

MeasureTime frame
Wound condition, including the presence or absence (yes/no) of granulation tissue, bleeding, pain, infection, and other wound complications or healing factors are evaluated. Timepoint: Every 48 hours. Method of measurement: Based on the scores of the variables and presence or absence (yes / no).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Omid Yazarlou

Mashhad University of Medical Sciences

Yazarlouom@mums.ac.ir+98 51 3802 2051

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026