Evaluating the effect of Vitamin E and Vitamin A on Chemotherapy-Induced Oral Mucositis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210916052498N1

Enrollment

Registered

2022-02-16

Start date

2022-02-19

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Mucositis. Oral mucositis (ulcerative) due to antineoplastic therapy

Interventions

Intervention group: patients receive vitamin E (100 mg/day) and vitamin A (25000 Unit/day) for 4 days ..

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Chemotherapy’s indicated No interactions between vitamins E and A and chemotherapy

Exclusion criteria

Exclusion criteria: Chemotherapy’s Contraindicated Interactions between vitamins E and A and chemotherapy

Design outcomes

Primary

Measure	Time frame
Oral Mucositis. Timepoint: Days 1, 7, 14 and 21 after starting cancer treatment. Method of measurement: Clinical examination by a dentist based on World Health Organization oral mucositis grading scale.	—

Secondary

Measure	Time frame
Pain severity. Timepoint: Days 1, 7, 14 and 21 after starting cancer treatment. Method of measurement: Visual Analogue Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohamad Amir Mohamadifard

Birjand University of Medical Sciences

mohamadamir_mohamadifard@yahoo.com+98 56 3162 6800

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026