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Effect of Vitamin B6 and L-acetyl-carnitin in Treatment of Carpal Tunnel Syndrome

Investigation of the Effect of Vitamin B6 Supplement in Comparison to L-acetyl-carnitine on Improvement of Patients with Carpal Tunnel Syndrome

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210915052494N1
Enrollment
60
Registered
2021-11-04
Start date
2021-11-06
Completion date
Unknown
Last updated
2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carpal tunnel syndrome.

Interventions

Intervention 1: First intervention group: 120 mg Vitamin B6 Janilous pharmaceutical Co. daily and splint for 10 weeks. Intervention 2: Second intervention group: 1500 mg L-acetyl-carnitine Dana pharma

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with Mild or Moderate Carpal Tunnel Syndrome Disease Proved with Electrodiagnostic Study within Last 2 Months Patients Age Ranges from 30-60

Exclusion criteria

Exclusion criteria: Severe Carpal Tunnel Syndrome Muscle Atrophy History of Carpal Tunnel Syndrome surgery History of Trauma History of Fracture History of Direct Injection of Carpal Tunnel History of Recent Usage of Corticosteroids and Analgesics Diabetes Collagen Vascular Disorders Rheumatologic Disorders Active Radiculopathy Past Medical History of Brucellosis Pregnancy Lactation Alcoholism Nerve Injury Neuropathy Inability in Communication and Fulfilling Questioners History of Allergic Reaction to Studied Medications History of Significant Liver, Kidney or Cardiovascular Disease Cancer History of Injection Around Wrist within 3 Last Months

Design outcomes

Primary

MeasureTime frame
Latency of Median sensory nerve action potential. Timepoint: Before the treatment, 10 and 18 weeks after beginning treatment. Method of measurement: Electromyography-Nerve conduction study (EMG-NCV) machine.;Score of clinical symptoms (like pain and paresthesia) in questionnaires. Timepoint: Before the treatment, 10 and 18 weeks after beginning treatment. Method of measurement: Visual Analogous Scale and Boston Carpal Tunnel Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNavid Parsa

Shiraz University of Medical Sciences

dr.parsanavid@gmail.com+98 21 2201 9258

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026