Augmenting cognitive behavioral therapy for obsessive-compulsive disorder with anti-disgust cognitive intervention

Augmenting efficacy of cognitive behavioral therapy with anti-disgust cognitive intervention on disgust propensity/ sensitivity, emotion acceptance, and OCD severity in patients with obsessive-compulsive disorder

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210914052475N1

Enrollment

Registered

2021-10-10

Start date

2021-10-17

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obsessive_compulsive disorder. Obsessive-compulsive disorder

Interventions

Intervention 1: Intervention group: cognitive-behavioral therapy plus anti-disgust cognitive intervention, 15 weekly sessions, time of each session: 90 minutes, case conceptualization, disgust-related

Eligibility

Sex/Gender

All

Age

19 Years to 40 Years

Inclusion criteria

Inclusion criteria: Being at least 18 years old in the beginning of the study. Having an education grade equal to 12 or more. Diagnose with contamination-based obsessive-compulsive disorder as a primary diagnosis. Having a stable dose of medication from 3 months before the beginning of the study. Completing informed constant form.

Exclusion criteria

Exclusion criteria: Diagnose with other comorbid psychiatric disorders or conditions except for major depressive disorder. Having a history of traumatic head injury or epilepsy.

Design outcomes

Primary

Measure	Time frame
Disgust propensity/ sensitivity. Timepoint: Pre-treatment, before exposure and response prevention sessions, post-treatment, three-month follow-up. Method of measurement: Disgust Propensity/ Sensitivity Scale (DPSS).;Obsessive-compulsive disorder severity. Timepoint: Pre-treatment, before exposure and response prevention sessions, post-treatment, three-month follow-up. Method of measurement: Yale-Brown Obsessive Compulsive Scale (Y-BOCS).;Emotion acceptance. Timepoint: Pre-treatment, before exposure and response prevention sessions, post-treatment, three-month follow-up. Method of measurement: Non-judging & non-reactivity sub-scales of Five Facets Mindfulness Questionnaire.	—

Measure

Time frame

Disgust propensity/ sensitivity. Timepoint: Pre-treatment, before exposure and response prevention sessions, post-treatment, three-month follow-up. Method of measurement: Disgust Propensity/ Sensitivity Scale (DPSS).;Obsessive-compulsive disorder severity. Timepoint: Pre-treatment, before exposure and response prevention sessions, post-treatment, three-month follow-up. Method of measurement: Yale-Brown Obsessive Compulsive Scale (Y-BOCS).;Emotion acceptance. Timepoint: Pre-treatment, before exposure and response prevention sessions, post-treatment, three-month follow-up. Method of measurement: Non-judging & non-reactivity sub-scales of Five Facets Mindfulness Questionnaire.

—

Secondary

Measure	Time frame
Acceptance rate of exposure and response prevention. Timepoint: Before exposure and response prevention sessions. Method of measurement: Percent of acceptance of exposure and response prevention.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Behzad Salmani

Kharazmi University

b.salmani1365@gmail.com+98 31 5568 3234

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026