Osteoarthritis of knee. Osteoarthritis of knee
Conditions
Interventions
Intervention 1: Intervention group1: Intravenous injection of transamine, 500 mg intravenously and before surgery. Intervention 2: Intervention group2: Intra-articular injection of transamine, 3 grams
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients candidate for total knee surgery in case of osteoarthritis
Exclusion criteria
Exclusion criteria: Known coagulopathy or hemorrhagic disorder Consumption of drugs that disrupt the coagulation system, including warfarin Patients prone to thromboembolic events due to primary internal problems, hepatic and renal dysfunction Patients include other concomitant skeletal disorders including hip osteoarthritis Traumatic patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding rate. Timepoint: Bleeding rate will be checked during surgery and before discharge. Method of measurement: The rate of bleeding will be measured based on the volume of the suction drain, the number of gauzes, hemovac drainage volume and hemoglobin level reduction.;Incidence of deep vein thrombosis. Timepoint: The incidence of deep vein thrombosis will be assessed at 2 weeks, 1, 3 and 6 months after surgery. Method of measurement: DVT incidence will be assessed by clinical examination and Doppler sonography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactJafar Soleimanpour Mokhtarmanand
Tabriz University of Medical Sciences
Outcome results
None listed