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Effect of rizatriptan in treatment of postictal headache

Treatment of post ictal headache by Rizatriptan, An open label cross-over clinical trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210908052414N1
Enrollment
30
Registered
2021-09-30
Start date
2021-10-06
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postictal headache. Other headache syndrome

Interventions

Intervention 1: Intervention group: 10 mg Rizatriptan from TEKAJ pharmaceutical company, immediately after one episodes of postictal headache will be administered for three months period . Interventio

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Patients with a current history of PIH according to International Headache Society (IHS) 2004 criteria. Patients with at least one predisposal headache attack per month for months prior to entering the study. The patients will be include to this study from epilepsy ward of Namazi hospital,Iran. The patients will be include to this study with at least age of 18 .

Exclusion criteria

Exclusion criteria: Patients have uncontrolled hypertension. Patients have ischemic heart disease. Patients have cardiac arrhythmias. Patients have previous stroke or transient ischemic attack. Patients have severe liver or renal impairment. Patients have any other severe or disabling medical condition. Patients have a history of alcohol or analgesic or psychotropic drug abuse. Patients have known hypersensitivity to study drugs. Patients who had demonstrated inadequate response to at least two triptans. Patients who currently use propranolol or ergotamine (and its derivatives) as a prophylactic agent. Patients who currently use MAO-inhibitors. Patients have psychogenetic non-epileptic seizure. Patients will be over 55 years old.

Design outcomes

Primary

MeasureTime frame
The Migraine Disability Assessment score. Timepoint: Before the intervention and half an hour to two hours after the start of taking Rizatriptan. Method of measurement: The Migraine Disability Assessment questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMina Shahisavandi

Shiraz University of Medical Sciences

stud2282140354@sums.ac.ir+98 71 3612 5841

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026