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Evaluation the effect of mouthwash containing propolis nanoparticles on the gum and teeth condition of orthodontic patients

Evaluation the effect of mouthwash containing propolis nanoparticles on plaque and gingival indices in fixed orthodontic patients.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210906052393N1
Enrollment
60
Registered
2021-10-25
Start date
2021-12-04
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Plaque index. Condition 2: Gingival index.

Interventions

Intervention 1: Intervention group: Use of three bottles containing 250 ml mouthwash containing propolis nanoparticles prepared in the Department of Pharmacology at Babol University of Medical Science

Sponsors

Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
13 Years to 19 Years

Inclusion criteria

Inclusion criteria: Age range 13-19 years Having proper oral hygiene (Plaque Index =2 ? Gingival Index= 2 the way of Sillness and Loe ? Loe and Sillness ) Complete and informed patient satisfaction

Exclusion criteria

Exclusion criteria: Existence of any systemic disease Pregnancy and lactation Smoking and alcohol consumption Existence of periodontal disease Having severe gingivitis and plaque accumulation History of any allergies to propolis or honey derivatives History of antibiotic consumption from two weeks before the intervention History of using any type of mouthwash during the month before the intervention

Design outcomes

Primary

MeasureTime frame
Plaque Index in Ramford teeth of fixed orthodontic patients. Timepoint: Before the intervention and one week after brushing and 21 days after starting to use mouthwash containing propolis nanoparticles. Method of measurement: Standardized periodontal probe.;Gingival Index in Ramford teeth of fixed orthodontic patients. Timepoint: Before the intervention and one week after brushing and 21 days after starting to use mouthwash containing propolis nanoparticles. Method of measurement: Standardized periodontal probe.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactValiolah Arash

Babol University of Medical Sciences

Vali-arash1344@yahoo.com+98 11 3220 7918

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026