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probiotics in the treatment of patient with chronic periodontitis

clinical, microbiological and IL-6 evaluation of probiotic lozenges in patients with chronic periodontitis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210905052375N1
Enrollment
24
Registered
2021-09-14
Start date
2021-10-20
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic periodontitis.

Interventions

Control group: Placebo group.

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 75 Years

Inclusion criteria

Inclusion criteria: patient have to have atleast 12 teeth atleast one of the tooth in each quadrant has (5-7mm) pocket gingival index >2 in each quadrant clinical attachmet loss >1mm radiographic evidence of bone loss

Exclusion criteria

Exclusion criteria: patients with systemic disease patients who were pregnant , lacking , smokers patients who had undergo periodontal or antibiotic treatment

Design outcomes

Primary

MeasureTime frame
Prevotella intermedia. Actinomycetemcomitans A. P.gingivalis.IL-6.gingival index. plaque index. clinical attachment loss. Timepoint: base line ,1 & 3 months. Method of measurement: plaque index by Sliness and LEO. gingival index by Leo and Sliness . attachment loss and pocket depth by william prob, Prevotella intermedia, Porphyromoas gingivalis. Actinomycetemcomitans A. by PCR & Real time PCR. IL-6 BY ELISA TEST.

Secondary

MeasureTime frame
. Timepoint: . Method of measurement: .

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr mahmood Ghasemi

Islamic Azad University

mahiran99@yahoo.com002122454571

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026