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Effects of rTMS and tDCS in balance of MS patients

Comparison of the effects of rTMS and tDCS combined with postural exercises on balance, postural stability and level of fear of falling in patients with Multiple sclerosis: a double-blind randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210905052374N1
Enrollment
60
Registered
2021-11-14
Start date
2022-04-21
Completion date
Unknown
Last updated
2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Sclerosis (MS).

Interventions

Participants in intervention group 1(cerebellar rTMS with postural training) receive 20 min of rTMS on their cerebellum during progressive postural training on the Biodex Balance System. Participants

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Clinically definite MS Age > 20 and <65 years Disability between 4.5 and 6.5 on the Expanded Disability Status Scale (EDSS) Walking ability according to the EDSS score A minimal leg spasticity score = 1 on the Modified Ashworth spasticity scale

Exclusion criteria

Exclusion criteria: Pregnant women Neurological, orthopedic and severe cardiac comorbidities Peripheral vestibular disorders (i.e., positional paroxysmal vertigo, Meniere’s disease, and acoustic neuroma) Blindness in one or both eyes Exacerbation in the past 2 months Exacerbation during the study

Design outcomes

Primary

MeasureTime frame
The stability indices at both static and dynamic levels of the Biodex Balance System. Timepoint: Before and after the intervention. Method of measurement: The Biodex Balance System (302-950 model, Biodex Medical Systems, Inc., New York, USA).

Secondary

MeasureTime frame
The Berg Balance Scale Score. Timepoint: Before and after the intervention. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMostafa Rahimi

Tehran University of Medical Sciences

rahimim@sina.tums.ac.ir+98 21 7753 3939

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026