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Comparison of the effect of dexmedetomidine and lower dose of neostigmine in pain relief after cesarean section with spinal anesthesia

Comparison of the effect of dexmedetomidine and lower dose of neostigmine in pain relief after cesarean section with spinal anesthesia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210904052371N4
Enrollment
102
Registered
2023-08-22
Start date
2023-08-17
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severity of pain. Pain, unspecified

Interventions

Intervention 1: Intervention group: 50 micrograms of neostigmine (manufactured by Subhan Pharmaceutical Company, Iran) plus 2.5 cc bupivacaine (manufactured by Elixir Pharmaceutical Company, Iran) 5%

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Women who had an elective cesarean delivery Women who are between 18 and 50 years old.

Exclusion criteria

Exclusion criteria: Patients who refused to participate, or after spinal anesthesia, the required sensory level was not established and were then subjected to general anesthesia. Patients with a history of allergy to any of the drugs used in this research History of drug addiction Moderate or severe heart, kidney, lung or nervous diseases Significant scoliosis or kyphosis Excessive obesity Blood coagulation disease Patients with height less than 130 cm or BMI more than 35

Design outcomes

Primary

MeasureTime frame
Intensity of pain. Timepoint: 0, 2, 4, 8 and 12 hours. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
Sedation rate. Timepoint: Hours 0, 2, 4, 8 and 12. Method of measurement: Using the Ramsay scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGoli Azzi

Mazandaran University of Medical Sciences

Gaezi@mazums.ac.ir+98 11 3336 1700

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026