Schizophrenia. Schizophrenia
Conditions
Interventions
Intervention 1: Intervention group: Patients with schizophrenia in the acute phase treated with 6 mg of risperidone manufactured by Abidi Company, which will receive 400 mg of celecoxib (200 mg twice
Sponsors
University of social welfare and rehabilitation sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients with schizophrenia in the acute phase Age range 18 to 65 years Receiving only one Antipsychotic drug (Risperidone) IQ greater than 70 Having the consent of the patient and his / her guardian to participate in the research
Exclusion criteria
Exclusion criteria: Having a debilitating physical illness patients with depression Received an electric shock in the last two weeks History of gastric ulcer or acute gastric bleeding Pregnancy and lactation No extra pyramidal symptoms in the study entry based on Simpson-Angus scale Drug, alcohol or drug abuse in the last 6 months (excluding nicotine) There is another diagnosis based on DSM5, including mood disorders and mental retardation Blindness and deafness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive symptoms of schizophrenia. Timepoint: Every 2 weeks to 8 weeks. Method of measurement: Positive And Negative Syndrome Scale.;Negative symptoms of schizophrenia. Timepoint: Every 2 weeks to 8 weeks. Method of measurement: Positive And Negative Syndrome Scale.;Cognitive symptoms of schizophrenia. Timepoint: Every 2 weeks to 8 weeks. Method of measurement: Montreal Cognitive Assessment Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects of medications. Timepoint: Every 2 weeks to 8 weeks. Method of measurement: questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarahnaz Moradzadeh
University of social welfare and rehabilitation sciences
Outcome results
None listed