Comparison of hospitalization time of patients with different treatments of deoulin nebulizer, deoulin nebulizer with inhalation spray and deoulin nebulizer and pulmicort simultaneously in patients with chronic obstructive pulmonary disease

Comparison of hospitalization time with deoulin nebulizer, deoulin nebulizer with inhalation spray and deoulin nebulizer and pulmicort simultaneously in patients with chronic obstructive pulmonary disease in the disease exacerbation stage

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210830052333N1

Enrollment

174

Registered

2021-10-13

Start date

2021-09-23

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic obstructive pulmonary disease. Chronic obstructive pulmonary disease with (acute) exacerbation

Interventions

Intervention 1: Intervention group 1: For the first intervention group, in addition to routine treatments including oxygen therapy, deoulin nebulization (salbutamol + ipratropium bromide) in a 2.5 ml

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients aged 18 to 80 years; Patients with confirmed diagnosis of chronic obstructive pulmonary disease by spirometric and clinical findings; Chronic illness for at least the last six months; Do not take any antibiotics for at least the last month; Conscious consent to participate in research.

Exclusion criteria

Exclusion criteria: Loss of consciousness; Severe restlessness; Severe respiratory distress with oxygen pressure less than 60 mm Hg and carbon dioxide pressure greater than 45 mm Hg in a venous gas sample; Severe heart failure; Pulmonary embolism; Use of any opium in the past month; Existence of severe infectious diseases of the respiratory tract for at least one month; History of any surgery on the respiratory tract.

Design outcomes

Primary

Measure	Time frame
The amount of hospitalization hours in the emergency department. Timepoint: Once an hour. Method of measurement: Count the hours of hospitalization.;Measuring the extent of disease severity reduction. Timepoint: Once an hour. Method of measurement: By counting the number of breaths per minute.;Maximum expiratory volume per the first second (FEV1). Timepoint: Once an hour. Method of measurement: Micromedical spirometer.	—

Measure

Time frame

The amount of hospitalization hours in the emergency department. Timepoint: Once an hour. Method of measurement: Count the hours of hospitalization.;Measuring the extent of disease severity reduction. Timepoint: Once an hour. Method of measurement: By counting the number of breaths per minute.;Maximum expiratory volume per the first second (FEV1). Timepoint: Once an hour. Method of measurement: Micromedical spirometer.

—

Secondary

Measure	Time frame
Measurement of arterial blood oxygen saturation. Timepoint: Once an hour. Method of measurement: Arterial blood oxygen measurement test with ABG device.;Measurement of venous blood carbon dioxide saturation. Timepoint: Once an hour. Method of measurement: Carbon dioxide test with ABG device.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactParisa Soleymani

Shahroud University of Medical Sciences

parisasoleimani1073@yahoo.com+98 23 3234 2000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026