Skip to content

The effect of selenium on cancer related-fatigue

Evaluation of the effect of selenium supplemention on cancer-related fatigue in outpatient cancer patients and comparison of it with placebo effect in control group

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210825052293N1
Enrollment
76
Registered
2021-10-03
Start date
2021-10-23
Completion date
Unknown
Last updated
2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer-related fatigue. Neoplasm-related fatigue

Interventions

Intervention 1: Intervention Group: In this group, patients will take one 200 µg capsule of Selenium Plus once daily for 2 weeks, after which they will complete the fatigue questionnaire. They will th

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 18 to 80 years of age To be able to read and write Definitive diagnosis of cancer which requires chemotherapy and has been confirmed with pathology findings and authenticated by an oncology subspecialist Not having another treatment regimen that has healing effect on fatigue To have cancer-related fatigue and score of 40 and above in fatigue questionnaire To tolerate oral medication To cooperate and agree with the study

Exclusion criteria

Exclusion criteria: Patients with known depression undergoing treatment Having anemia Having a disease that prevents patient from continuing participation in study When more than 20% of the questionnaire has not been completed Pregnancy and lactation Renal failure Taking medications such as baloxavir, marboxil, deferiprone, cabotegravir, bisphosphonate derivatives, bictegravir, dolutegravir, eltrombopag, trientine, raltegravir, penicillamine, elvitegravir Known allergy to selenium Hypothyroidism Skin cancer and individulas at high risk for developing squamous cell carcinoma

Design outcomes

Primary

MeasureTime frame
Cancer-related fatigue. Timepoint: Zero, 2 weeks, 4 weeks. Method of measurement: Multivariable questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Mansouri

Esfahan University of Medical Sciences

alireza.mansory@gmail.com+98 31 3776 2744

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026