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Efficacy of 5% cysteamine vs 4% hydroquinone in melasma

Efficacy of 5% cysteamine vs 4% hydroquinone in melasma

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210823052264N13
Enrollment
228
Registered
2025-01-09
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Melasma.

Interventions

Intervention 1: Intervention group: Group A will be given 5% cysteamine at night. Intervention 2: Intervention group: Group B will be given 4% hydroquinone at night.

Sponsors

Cmh Quetta
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Adults aged 18-50 years with a clinical diagnosis of mild to moderate melasma (MASI score 4-24). Patients with Fitzpatrick skin types III to V . Patients with epidermal and dermal hyperpigmentation. Patients willing to use sun protection and adhere to treatment protocols.

Exclusion criteria

Exclusion criteria: Patients with chronic underlying diseases like eczema Pregnant and breastfeeding Patients allergic to cysteamine and hydroquinone

Design outcomes

Primary

MeasureTime frame
Change in MASI score from baseline. Timepoint: Before intervention, 1 month,2 month and 3 month. Method of measurement: Photographic evidence and MASI score.

Countries

Pakistan

Contacts

Public ContactSummra Pervaiz

Cmh Quetta

summra.hassan6@gmail.com+92 304 8075604

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026