To Compare the efficacy of Transamic acid (TA) injection vs Hydroquinone, Flucinolone acetonide and Tretinoin for melasma

To Compare the efficacy of Transamic acid (TA) mesotherapy vs Hydroquinone, Flucinolone acetonide and Tretinoin for melasma

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210823052264N1

Enrollment

Registered

2021-09-29

Start date

2021-07-10

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Melasma.

Interventions

Intervention 1: Intervention group: In group A transamic acid is injected intradermally into melasma areas 1cm intervals every 2 weeks for 3 months. Intervention 2: Intervention group: Group B will b

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Males and females 18-55 years with facial melasma

Exclusion criteria

Exclusion criteria: Patients who has bleeding disorders, pregnant women and lactating mothers.

Design outcomes

Primary

Measure	Time frame
The degree of melasma treatment. Timepoint: Before treatment, at 4th, 8th and 12th week during the treatment. Method of measurement: MASI Score.	—

Countries

Pakistan

Contacts

Public ContactDr Muhammad Rahim

PNS SHIFA

drrahimachak@gmail.com+92 21 48506592

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026