Metastatic colon cancer. Malignant neoplasm of colon
Conditions
Interventions
Intervention 1: Intervention group: Standard chemotherapy drugs for colon cancer + memantine Memantine, which is our intervention, will be administered ora
Sponsors
Oroumia University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: All patients over 18 years of age with metastatic colon cancer
Exclusion criteria
Exclusion criteria: Severe renal failure Liver failure (more than 5-fold increase in liver enzymes) History of memantine allergy History of seizures Cardiovascular disease Eye diseases Concomitant use of drugs that alter the pH of the urine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of life in patient with colon cancer. Timepoint: Beginning and end of the study (third month). Method of measurement: QLQ-C30 Questionnaire.;The size of tumor in patients with colon cancer. Timepoint: Beginning and end of the study (third month). Method of measurement: CT scan. | — |
Secondary
| Measure | Time frame |
|---|---|
| Vascular endothelial growth factor (VEGF). Timepoint: Beginning and end of the study (third month). Method of measurement: ELISA kit.;Carcinoembryonic Antigen (CEA). Timepoint: Beginning and end of the study (third month). Method of measurement: ELISA kit.;Body Mass Index (BMI). Timepoint: Beginning and end of the study (third month). Method of measurement: weight kg/height m2. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Hamid Soraya
Oroumia University of Medical Sciences
Outcome results
None listed