Evaluation of the Effect of an Innovative Combination Solution Containing: Amoxicillin, Betamethasone and Ibuprofen on Controlling pain, Swelling and Infection Caused by Wisdom Tooth Surgery

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210818052227N1

Enrollment

Registered

2021-10-26

Start date

2021-10-23

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Extraction of wisdom teeth. Embedded and impacted teeth

Interventions

Intervention 1: Intervention group: Inserting gelfoam containing amoxicillin, betamethasone and ibuprofen into the silent tooth. Turn until it is impregnated with jelfum to have a longer effect and sl

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Has erupted wisdom teeth Absence of systemic disease Proper oral hygiene

Exclusion criteria

Exclusion criteria: systemic disease Improper oral hygiene

Design outcomes

Primary

Measure	Time frame
Reducing pain. Timepoint: Patients are told to report the problem in case of severe pain and discomfort. The VAS form is given to patients to record the amount of pain: 12 and 24 hours after surgery and on 2-3-4-5-6-7 days after surgery. Method of measurement: Through the VAS chart.;Inflammation control. Timepoint: The same amount of swelling is measured 42 hours after surgery and on the morning of the 3rd and 7th days after surgery. Method of measurement: Facial width is calculated by marking 5 pink spaces on a piece of yarn and then measuring it with a ruler. Horizontal distance: The distance between the corner of the lip to the junction of the auricular lobule (Earlobe) on the same side and the piece of thread follow the convexity of the cheek. Vertical: The distance between the outer canthus of the eye to the mandibular angle of the same side and the piece of thread follow the convexity of the face. Mile: The distance from the corner of the lip to the angle of the mandible on the same side and the piece of floss should follow the possible convexity of the face (swelling after surgery). During these three measurements, the patient lies supine on the unit and the receiver is on the desired side.;Infection control. Timepoint: In terms of pus, heat and redness in the desired area. Method of measurement: Zero and one technique (zero: no infection and one: infection).	—

Measure

Time frame

Reducing pain. Timepoint: Patients are told to report the problem in case of severe pain and discomfort. The VAS form is given to patients to record the amount of pain: 12 and 24 hours after surgery and on 2-3-4-5-6-7 days after surgery. Method of measurement: Through the VAS chart.;Inflammation control. Timepoint: The same amount of swelling is measured 42 hours after surgery and on the morning of the 3rd and 7th days after surgery. Method of measurement: Facial width is calculated by marking 5 pink spaces on a piece of yarn and then measuring it with a ruler. Horizontal distance: The distance between the corner of the lip to the junction of the auricular lobule (Earlobe) on the same side and the piece of thread follow the convexity of the cheek. Vertical: The distance between the outer canthus of the eye to the mandibular angle of the same side and the piece of thread follow the convexity of the face. Mile: The distance from the corner of the lip to the angle of the mandible on the same side and the piece of floss should follow the possible convexity of the face (swelling after surgery). During these three measurements, the patient lies supine on the unit and the receiver is on the desired side.;Infection control. Timepoint: In terms of pus, heat and redness in the desired area. Method of measurement: Zero and one technique (zero: no infection and one: infection).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactPouya Mansourian

Semnan University of Medical Sciences

mansourian77pouya@gmail.com+98 23 3522 5936

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026