Colonoscopy preparation and probiotic use on the severity of constipation

The effect of colonoscopy preparation and probiotic consumption on the severity of functional constipation of the gastrointestinal tract (functional constipation and irritable bowel syndrome with constipation pattern)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210817052219N1

Enrollment

Registered

2021-10-13

Start date

2021-11-20

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Functional constipation. Constipation

Interventions

Intervention 1: Intervention group: In this group, patients will receive PEG powder before colonoscopy. After colonoscopy, patients receive two bio-flora (lactic acid bacteria) capsules from Tak Gene

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Having functional constipation in people over 18 years according to ROME IV criteria Having irritable bowel syndrome with constipation patternaccording to ROME IV criteria Free and informed written consent to participate in the study Age over 18 years

Exclusion criteria

Exclusion criteria: Any history of chronic inflammatory disease or structural disease of the gastrointestinal tract Any serious physical problems or illnesses such as inflammation or malignancy Any physical problems that prevent you from doing physical activity Addiction to drugs or sleeping pills History of chronic diseases such as diabetes

Design outcomes

Primary

Measure	Time frame
Constipation score. Timepoint: Before receiving the colonoscopy preparation and then in weeks 2, 4, 8 after the start of the intervention and 4 weeks after the end of the intervention (week 12). Method of measurement: ROM 3 criteria.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Soheilipour

Esfahan University of Medical Sciences

leila.kh7501256@yahoo.com+98 31 3222 2127

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026