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"The Effect of Garlic Extract on Lowering Blood Pressure in Prehypertensive Individuals"

The Effects of Garlic Extract(Dosage Form) on Blood Pressure in Pre-Hypertensive Individuals and Measuring Lipid Profiles and Nitric Oxide Metabolites in the Individuals

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210815052186N1
Enrollment
110
Registered
2021-09-05
Start date
2021-09-22
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prehypertension. Essential (primary) hypertension

Interventions

Intervention 1: Intervention group: The intervention group will receive a 500 mg capsule containing standardized garlic extract (allicin, The exact dose will be determined during the practical work),

Sponsors

Khoram-Abad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: "People in Their 30s and 70s (Men and Women) Who Have Recently or At Least Three Months Received a Diagnosis of Pre-hypertension"

Exclusion criteria

Exclusion criteria: People with Allergies to Garlic and its Side Effects People with Cardiovascular Problems and Diseases. Patients Who Have Previously been Diagnosed with High Blood Pressure and are Taking Antihypertensive Drugs. People with Diabetes. People who Have recently had surgery. People Who Have Recently Received Anesthetics. People with Blood Disorders Who are Taking Anticoagulants People with a History of Gallstones. People with a History of Hypoglycemia. Pregnant and Lactating Women

Design outcomes

Primary

MeasureTime frame
Blood pressure (Systolic, Diastolic, Pulse pressure, Mean arterial pressure). Timepoint: "Measurement of blood pressure at the beginning of the study (before the intervention) and 4 weeks after the intervention and at the end of the study (8 weeks after the start of the study)". Method of measurement: "Mercury Barometer".;Nitric oxide metabolite level. Timepoint: Before the intervention, four weeks after the intervention, end of the intervention (eight weeks after the intervention). Method of measurement: Grace method.;Triglyceride. Timepoint: Before the intervention, four weeks after the intervention, end of the intervention (eight weeks after the intervention). Method of measurement: Autoanalyzer device.;Cholesterol. Timepoint: Before the intervention, four weeks after the intervention, end of the intervention (eight weeks after the intervention). Method of measurement: Autoanalyzer device.;Low Density Lipoprotein (LDL). Timepoint: Before the intervention, four weeks after the intervention, end of the intervention (eight weeks after the intervention). Method of measurement: Autoanalyzer device.;High Density Lipoprotein (HDL). Timepoint: Before the intervention, four weeks after the intervention, end of the intervention (eight weeks after the intervention). Method of measurement: Autoanalyzer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAfshin Nazari

Khoram-Abad University of Medical Sciences

nazary257@yahoo.com+98 66 3332 3704

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026