The effect of "Berberpim®" syrup on Non-alcoholic fatty liver disease

Formulation and evaluation of the effectiveness of "Berberpim®" syrup in patients with Non-alcoholic fatty liver disease: A randomized clinical trial study

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210814052178N1

Enrollment

Registered

2021-09-02

Start date

2021-11-06

Completion date

Unknown

Last updated

2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-alcoholic fatty liver disease. Fatty (change of) liver, not elsewhere classified

Interventions

Intervention 1: Intervention group: Twice daily use 10 cc of Berberpim syrup to move for 3 months. Intervention 2: Control group: Twice daily use of 10 cc placebo for 3 months.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years Patients with grade I and II Non-alcoholic fatty liver disease according to the results of ultrasound, clinical interview, increase in liver enzymes and elimination of other causes this disease affects Non-alcoholic fatty liver

Exclusion criteria

Exclusion criteria: Patients with Hepatitis Wilson's disease People who drink alcohol People with type I diabetes and type II diabetes who have been taking the drug for a year Consumers of drugs that affect the level of liver enzymes such as Statins and Acetaminophen in high doses

Design outcomes

Primary

Measure	Time frame
Alanine transaminase. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;Aspartate transaminase. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;Triglyceride. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;Cholesterol. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;High-density lipoprotein. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;Low-density lipoprotein. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;Fasting blood sugar. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;Platelets. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;Vitamin D. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;C-Reactive Protein. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;Erythrocyte Sedimentation Rate. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;Weight. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Weighing scales.;Abdominal circumference. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Tapeline.;Body mass index. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Special formula.	—

Measure

Time frame

Alanine transaminase. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;Aspartate transaminase. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;Triglyceride. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;Cholesterol. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;High-density lipoprotein. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;Low-density lipoprotein. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;Fasting blood sugar. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;Platelets. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;Vitamin D. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;C-Reactive Protein. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;Erythrocyte Sedimentation Rate. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Blood Test.;Weight. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Weighing scales.;Abdominal circumference. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Tapeline.;Body mass index. Timepoint: Before intervention, 3 months after intervention. Method of measurement: Special formula.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKiana Anboohgol

Kermanshah University of Medical Sciences

Kanboohgol@yahoo.com+98 35 24402

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026