The effect of pulmonary rehabilitation, inspiratory muscle training and therapeutic exercise training in patients with diaphragmdysfunction

The effect of pulmonary rehabilitation, inspiratory muscle training and therapeutic exercise training on the phrenic nerve conduction study and diaphragm muscle ultrasound findings in patients with diaphragm paralysis

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210813052172N1

Enrollment

100

Registered

2022-02-08

Start date

2022-03-21

Completion date

Unknown

Last updated

2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with diaphragm paralysis. Disorders of diaphragm

Interventions

Intervention 1: Intervention group: In patients with unilateral dysfunction of the diaphragm, a pulmonary function test and then nerve conduction study of the phrenic nerve is performed. The next step

Eligibility

Sex/Gender

All

Age

12 Years to No maximum

Inclusion criteria

Inclusion criteria: Elevation of the diaphragm evident on chest X-ray Elevation of the diaphragm evident on CT scan of the lung Age over 12 years

Exclusion criteria

Exclusion criteria: Individual dissatisfaction with participation in the study The patient's inability to perform the desired exercises

Design outcomes

Primary

Measure	Time frame
Phrenic nerve amplitude. Timepoint: Before training, three and six months later. Method of measurement: Electromyogram and nerve conduction study.;Phrenic nerve latency. Timepoint: Before training, three and six months later. Method of measurement: Electromyogram and nerve conduction study.;Diaphragm muscle thickness. Timepoint: Before training, three and six months later. Method of measurement: Ultrasound device.;Diaphragm movement speed. Timepoint: Before training, three and six months later. Method of measurement: six minute walk test.;Forced Expiratory Volume, Forced Expiratory Volume in First Second. Timepoint: Before training, three and six months later. Method of measurement: Spirometry.;Maximum expiratory pressure and maximum inspiratory pressure. Timepoint: Before training, three and six months later. Method of measurement: Body box.	—

Measure

Time frame

Phrenic nerve amplitude. Timepoint: Before training, three and six months later. Method of measurement: Electromyogram and nerve conduction study.;Phrenic nerve latency. Timepoint: Before training, three and six months later. Method of measurement: Electromyogram and nerve conduction study.;Diaphragm muscle thickness. Timepoint: Before training, three and six months later. Method of measurement: Ultrasound device.;Diaphragm movement speed. Timepoint: Before training, three and six months later. Method of measurement: six minute walk test.;Forced Expiratory Volume, Forced Expiratory Volume in First Second. Timepoint: Before training, three and six months later. Method of measurement: Spirometry.;Maximum expiratory pressure and maximum inspiratory pressure. Timepoint: Before training, three and six months later. Method of measurement: Body box.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoume Zoghali

Shahid Beheshti University of Medical Sciences

masoumezoghali@sbmu.ac.ir+98 21 2610 5050

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026