Comparative effect of sufentanil over morphine in the prevention of hypertension and tachycardia

Comparative study of the effect of sufentanil and lidocaine mixture in comparison with morphine and lidocaine mixture in the prevention of hypertension and tachycardia in patients under general anesthesia in Khatam Al-Anbia hospital in Shahroud in 1399_1400

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210807052100N1

Enrollment

100

Registered

2021-09-03

Start date

2021-01-20

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholecystitis.

Interventions

Intervention 1: Intervention group1: -Sofentanil: 0.06-0.05 mg per kg body weightLidocaine: 1-2 mg per kg body weight. Intervention 2: Intervention group 2: Lidocaine: 1-2 mg/kg, Morphine: 2-3 mg/kg.

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Candidate for laparoscopic cholecystectomy Age between 18 and 65 years

Exclusion criteria

Exclusion criteria: Having high blood pressure Cesarean History of heart disease including CHF, IHD. COPD Allergy to opium Asthma History of invasive diagnostic and therapeutic action on the heart

Design outcomes

Primary

Measure	Time frame
Blood pressure changes. Timepoint: In !5 minutes before, zero and after 5, 10 and 20 minutes. Method of measurement: Cardiac monitoring of blood pressure and heart rate.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Yusef Kolukhi

Islamic Azad University

Navid.pan.np@gmail.com+98 23 3239 2661

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026