Major Depressive Disorder. Major depressive disorder, recurrent, unspecified
Conditions
Interventions
Intervention 1: Intervention group: Patients aged 25 to 60 years who were diagnosed with major depressive disorder based on the DSM-V criteria and did not respond to at least 2 antidepressants, receiv
Sponsors
Zanjan University of Medical Sciences
Vice Chancellor for Research, Zanjan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
25 Years to 60 Years
Inclusion criteria
Inclusion criteria: Diagnosis of major depressive disorder based on DSMV criteria Failure to respond to at least 2 antidepressants with sufficient therapeutic dose The criterion of Montgomery-Asberg at least 25
Exclusion criteria
Exclusion criteria: Having skull masses Having history of HTN Having history of IHD Having a recent or past psychotic disorder Consumption of recent substances Pregnancy Existence of unstable medical disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression severity based on Montgomery-Asberg. Timepoint: Before injecting the drug-Immediately after drug injection-1 hour after drug injection-4 hour after drug injection-1 day after drug injection-3 day after drug injection-7 day after drug injection-1 month after drug injection-2 month after drug injection. Method of measurement: Based on Montgomery-Asberg questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Suicide idea. Timepoint: Before the drug injection-after the drug injection. Method of measurement: Based on the Beck questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarnaz Taherkhani
Zanjan University of Medical Sciences
Outcome results
None listed