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Evaluation of the effect of synbiotic on complications after gastrointestinal surgery

Evaluation of the effect of synbiotic on complications after gastrointestinal surgery - randomized clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210804052083N1
Enrollment
40
Registered
2022-04-10
Start date
2022-03-21
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Benign neoplasms of the large intestine, rectum, anus and anal canal. Condition 2: Benign neoplasms of other parts and obscure parts of the gastrointestinal tract. Condition 3: Malignant mesothelial and soft tissue neoplasms. Condition 4: Carcinoma in situ of other gastrointestinal organs and unspecified gastrointestinal organs. Condition 5: Carcinoma in situ of oral cavity, oesophagus and stomach. Condition 6: Benign carcinoma of the colon, rectum, anus, and anal canal. Condition 7

Interventions

Intervention 1: Group A: In the intervention group, patients will receive lactocare capsules 500mg (zist takhmir pharmaceutical company) 7 days before surgery and as soon as they start oral administra

Sponsors

Bandare-abbas University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patient satisfaction for inclusion in the study need for elective gastrointestinal surgery having a proper nutritional status for surgery

Exclusion criteria

Exclusion criteria: Patient dissatisfaction to enter the study patient with underlying diseases such as diabetes, coagulation disorders, congenital or acquired immunodeficiency, liver cirrhosis, renal failure, acute pancreatitis

Design outcomes

Primary

MeasureTime frame
Postoperative ileus. Timepoint: From the day of operation to the day of discharge. Method of measurement: The first gas passing after surgery by day.;Number of days of hospitalization after surgery. Timepoint: From the day of operation to the day of discharge. Method of measurement: By day.;Time to start oral feeding. Timepoint: From the day of operation to the day of discharge. Method of measurement: The patient's first day of oral feeding after surgery.;Postoperative infection / Abdominal abscess / Wound infection. Timepoint: From the day of operation to the day of discharge. Method of measurement: Physical examination.;Postoperative pneumonia. Timepoint: From the day of operation to the day of discharge. Method of measurement: Clinical examination and chest radiography at the discretion of the physician.;Anastomosis leak. Timepoint: From the day of operation to the day of discharge. Method of measurement: Physical examination.;Heart failure / Kidney failure / Liver disfunction. Timepoint: From the day of operation to the day of discharge. Method of measurement: Request laboratory tests if there are clinical signs.;Nausea and vomiting. Timepoint: From the day of operation to the day of discharge. Method of measurement: Clinical examination and patient complaints.;Pain and dyspepsia. Timepoint: From the day of operation to the day of discharge. Method of measurement: Clinical examination and patient complaints.;Fever. Timepoint: From the day of operation to the day of discharge. Method of measurement: Physical examination.;Mortality in 30 days after surgery. Timepoint: From the day of surgery to 30 days after surgery. Method of measurement: Death report by physician.;SIRS. Timepoint: From the day of operation to the day of discharge. Method of measurement: Request tests if there are clinical signs.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAhmadreza Karimi

Bandare-abbas University of Medical Sciences

karimi.ahmadreza@hums.ac.ir0763372145

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026