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Effect of preemptive ibuprofen analgesic compared to placebo on pain perception associated with the placement of temporary anchorage devices (TADs), A double blinded randomised clinical trial

Effect of preemptive ibuprofen analgesic compared to placebo on pain perception associated with the placement of temporary anchorage devices (TADs), A double blinded randomised clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210803052059N1
Enrollment
46
Registered
2022-03-07
Start date
2022-02-09
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malocclusion, Dental crowding.. Anomalies of dental relationship

Interventions

Intervention 1: Intervention group: 25 participants, the medication (400 mg Ibuprofen (Advil? Pfizer Inc.)) will be given to the first groups thirty minutes before the TAD placement. Intervention 2: C

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
13 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients treated with fixed orthodontic appliances Patients that only need one TAD in the posterior part of the maxilla Patients that will agree to participate in the clinical trial

Exclusion criteria

Exclusion criteria: Patients with poor oral hygiene or severe gingivitis Patients with systemic diseases Patients who currently are using other pain killer medications Patients who are allergic to any of TAD, Ibuprofen, or Placebo medication Patients who can not swallow

Design outcomes

Primary

MeasureTime frame
Severity and type of pain during different times. Timepoint: severity and type of pain will be recorded at the following times: immediately after TAD placement (T1), 1 hour after TAD placement (T2), 12 hours after TAD placement (T3), 24 hour after TAD placement (T4). Method of measurement: The patients will be asked to fill a questionnaire form, this form is consisted of a Persian translated copy of short form of McGill Pain questionnaire (SF-MPQ).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactArman Mohammadi Shayan

Tabriz University of Medical Sciences

mohammadishayan@tbzmed.ac.ir+98 41 3661 4341

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026