Condition 1: Effect of Duloxetine on the Mental State of Patients (Anxiety) with Diabetic Neuropathy. Condition 2: Effect of Duloxetine on the Mental State of Patients (Depression) with Diabetic Neuropathy. Diabetes mellitus due to underlying condition with diabetic autonomic (poly)neuropathy Diabetes mellitus due to underlying condition with diabetic autonomic (poly)neuropathy
Conditions
Interventions
Intervention group: A group treated with duloxetine in the form of 30 mg oral capsules,Twice a day (every 12 hours) for 30 days.
Sponsors
Islamic Azad University
Eligibility
Sex/Gender
All
Age
20 Years to 85 Years
Inclusion criteria
Inclusion criteria: Age between 20 to 85 Diabetic patients with sensory diabetic neuropathy in organs with symptoms of anxiety or depression (ASA patients 1-3)
Exclusion criteria
Exclusion criteria: Lack of patient cooperation in proper drug use or response Drug intolerance by the patient Pregnant women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determination mental state (anxiety / depression) of patients with diabetic neuropathy based on Beck questionnaire. Timepoint: Determining the score of anxiety and depression at the beginning of the study (before the intervention) and 30 days after taking duloxetine. Method of measurement: Beck Anxiety and Depression Inventory questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Intensity of pain Fingers or toes based on VAS scale. Timepoint: Determining the score of anxiety and depression at the beginning of the study (before the intervention) and 30 days after taking Duloxetine. Method of measurement: Visual Analogue Scale.;Frequency of adverse drug complications (Duloxetine). Timepoint: 30 days after taking Duloxetine. Method of measurement: ?Check list including possible adverse drug reactions following Duloxetine. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Masoud Khoshbin
Islamic Azad University
Outcome results
None listed