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Effect of diazepam and haloperidol in controlling agitation

Comparison of the effect of diazepam alone and in combination with haloperidol in controlling agitation caused by stimulants

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210720051946N6
Enrollment
60
Registered
2024-01-07
Start date
2023-12-14
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

poisoned patients. F00-F99

Interventions

Intervention 1: Intervention group: Diazepam (10 mg) + Haloperidol (5 mg). Intervention 2: Control group: Diazepam (10 mg).

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria include consent to participate in the study, diagnosis of agitation with DSM 5 1 criteria following the consumption of stimulants and age over 18 years.

Exclusion criteria

Exclusion criteria: On the other hand, another set of indicators is considered as exclusion criteria, these exclusion criteria include lack of consent to participate in the study, the presence of risk factors for cognitive disorders such as the presence of brain and nerve diseases (such as seizures, dementia, Parkinson's). ), a history of moderate to severe head trauma, a history of head trauma, decreased level of consciousness, glaucoma, psychosis, moderate to severe dependence on other substances, heart diseases such as long QT 2, and observation of the side effects of the drugs used.

Design outcomes

Primary

MeasureTime frame
Agitation. Timepoint: 0,10,15,30 min. Method of measurement: richmond questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPeyman Erfan Talab Evini

Shahid Beheshti University of Medical Sciences

peyman1346erfan@sbmu.ac.ir+98 21 5102 5000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026