Assessment of Intravenous Levocarnitine on the mortality and morbidity of patients with aluminum phosphide intoxication

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210720051946N1

Enrollment

Registered

2022-04-20

Start date

2020-06-30

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

aluminum phosphide poisoning. Toxic effect of pesticides

Interventions

Intervention 1: Intervention group: L-Carnitine 1 gram every 8 hours intravenously with standard care. Intervention 2: Control group: Standard care (a vasopressor with sodium bicarbonate or potassium

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: aluminum phosphide intoxication Positive silver nitrate test Systolic blood pressure lower than 90 mmHg Serum bicarbonate less than 15 mEq/L Blood pH lower than 7.2 Cardiac output of 15 and above

Exclusion criteria

Exclusion criteria: Patients or caregivers who do not provide written informed consent

Design outcomes

Primary

Measure	Time frame
24-hour mortality. Timepoint: assessment of death within 24 hours after arrival to the hospital. Method of measurement: patient medical record.	—

Secondary

Measure	Time frame
Peripheral blood pH. Timepoint: every three hours. Method of measurement: Venous blood gas.;Peripheral Blood HCO3. Timepoint: every three hours. Method of measurement: Venous blood gas.;Blood pressure. Timepoint: every three hours. Method of measurement: sphygmomanometer.;Vasopressor administration. Timepoint: every three hours. Method of measurement: Patient medical record.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Hoorvash Farajidana

Alborz university of medical sciences

hoorvash88@gmail.com+98 26 3419 7000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026