Helicobacter Pylori. Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere
Conditions
Interventions
Intervention 1: Control group: Patients in the control group will be treated with the four-drug regimen of two capsules of amoxicillin 500 every 12 hours,one clarithromycin 500 capsules every 12 hours
Sponsors
Ghoum University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Infection with Helicobacter pylori based on urease test results on endoscopic tissue samples Age over 18 years Indications for Helicobacter pylori eradication treatment Satisfaction to enter the project and perform endoscopy
Exclusion criteria
Exclusion criteria: Dissatisfaction with participating in the project Dissatisfaction or possibility of endoscopy No endoscopic indication History of treatment failure History of drug allergy or contraindication to amoxicillin, clarithromycin and bismuth Take another herbal medicine or probiotic at the same time
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradicate Helicobacter pylori infection. Timepoint: Patients in the intervention group underwent a four-drug regimen for Helicobacter pylori eradication, including amoxicillin capsules plus clarithromycin capsules and bismuth tablets plus pantoprazole, plus 2 capsules piloshot daily,and patients in the control group will be treated with the above four-drug regimen along with 2 placebo tablets of Pilochat drug daily. The duration of the treatment period will be 14 days. Helicobacter pylori will be followed up after treatment. Method of measurement: Bacterial fecal antigen test.;Drug side effects. Timepoint: Patients in the intervention group underwent a four-drug regimen for Helicobacter pylori eradication, including amoxicillin capsules plus clarithromycin capsules and bismuth tablets plus pantoprazole, plus 2 capsules piloshot daily,and patients in the control group will be treated with the above four-drug regimen along with 2 placebo tablets of Pilochat drug daily. The duration of the treatment period will be 14 days. Helicobacter pylori will be followed up after treatment. Method of measurement: questionnaire.;Clinical symptoms after treatment. Timepoint: Patients in the intervention group underwent a four-drug regimen for Helicobacter pylori eradication, including amoxicillin capsules plus clarithromycin capsules and bismuth tablets plus pantoprazole, plus 2 capsules piloshot daily,and patients in the control group will be treated with the above four-drug regimen along with 2 placebo tablets of Pilochat drug daily. The duration of the treatment period will be 14 days. Helicobacter pylori will be followed up after treatment. Method of measurement: questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahdi Pezeshki Modares
Ghoum University of Medical Sciences
Outcome results
None listed