Antimicrobial efficacy of "essential oil of Ocimum sanctum" compared with triple antibiotic paste, CHX-TAP mixture, and formocerosol as intracanal medicaments in primary molars: A clinical trial

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210718051926N3

Enrollment

120

Registered

2026-02-18

Start date

2026-04-14

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulpectomy in primary molars.

Interventions

Intervention group: patients who receive ocimum sanctum in root canals.

Eligibility

Sex/Gender

All

Age

7 Years to 9 Years

Inclusion criteria

Inclusion criteria: • Patients between 4-9 years of age- Teeth exhibiting clear clinical signs of furcal abscess/periapical abscess/nasal polyps- necrotic primary molars- Radiographic changes revealed in the periapical area- Strategically important teeth- Presence of at least 2/3rd of root length

Exclusion criteria

Exclusion criteria: • Patients with any severe systemic disease - Patient undergoing long-term antibiotic therapy, steroid therapy, antiepileptic therapy, etc.- Patients with special healthcare needs- atopic patients- intensive oral pathologies- Unrestorable crowns- uncooperative patients

Design outcomes

Primary

Measure	Time frame
Reduction in microbial count in root canals. Timepoint: seven days. Method of measurement: aerobic and anaerobic microbiological cultures.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactdr bahareh nazemi salman

Zanjan University of Medical Sciences

dr.b.nazemi@gmail.com+98 24 3333 7643

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026