Chronic anal fissure. Chronic anal fissure
Conditions
Interventions
Intervention 1: Intervention group: treatment is in the form of pediatric glycerin suppository 1 g, 5 minutes after using lidocaine ointment and diltiazem every morning, and the use of lidocaine and
Some lubricant gel can be impregnated around the suppository to facilitate passage. Iran Najo Pharmaceutical Co. Tehran-Iran. Intervention 2: Control group: Treatment of fissure in thi
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Posterior or anterior fissure No previous history of autoimmune disease No history of immunodeficiency disease No history of previous gastrointestinal cancer People over 40 years of age with normal colonoscopy No risk factor including weight loss during 6 Last month No anorexia No history of gastrointestinal genetic cancers (such as FAP, HNPCC) If a person is positive with FIT or a person with iron deficiency anemia, if he has a normal colonoscopy and endoscopy can be included in the study
Exclusion criteria
Exclusion criteria: Reluctance to continue treatment smoking and spicy spices
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) Patients' pain score 2) Percentage of constipation improvement in the intervention group 3) Percentage of bleeding improvement in the intervention group 4) Percentage of improvement of incomplete stool discharge in the intervention group 5) Percentage of burning sensation in the intervention group 6) Percentage of itching improvement in the intervention group. Timepoint: 1) Pain score of the intervention group with the control group before and after treatment (first day, second weekend, fourth weekend) 2) constipation of the intervention group and control group (first day, second weekend, fourth weekend) 3) bleeding Intervention group and control group (first day, second weekend, fourth weekend) 4) incomplete defecation of the intervention group and control group (first day, second weekend, fourth weekend) 5) burning of the intervention group and control group (first day , Second weekend, fourth weekend) 6) itching Intervention and control group (first day, second weekend, fourth weekend). Method of measurement: 1) Measuring pain through Visual Analogue Scale 2) Percentage of improvement of constipation through checklist 3) Percentage of improvement of bleeding through checklist 4) Percentage of improvement of incomplete stool discharge through checklist | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Headache improvement 2) Quality of life indicators score. Timepoint: 1) Improvement of headache after treatment (second weekend, fourth weekend) 2) score of quality of life indicators before and after treatment (first day, second weekend, fourth weekend). Method of measurement: 1) Improvement of headache through a checklist 2) Score of quality of life indicators based on WHO-QOL 100 questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Eslamin
Esfahan University of Medical Sciences
Outcome results
None listed