Skip to content

Succinylcholine and Rocuronium effects on the rate of emergence agitation

A comparison of Succinylcholine and Rocuronium effects on the rate of emergence agitation when awakening in patients undergoing direct diagnostic laryngoscopy under general anesthesia

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210714051888N1
Enrollment
48
Registered
2021-12-19
Start date
2021-11-22
Completion date
Unknown
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diagnostic biopsy under direct laryngoscopy.

Interventions

Intervention 1: Intervention group 1: succinylcholine.The first group will receive 3 micrograms / kg of fentanyl and 0.5 mg / kg of lidocaine for premedication, and will be induced with 1 mg / kg of s

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients 20 to 50 years without a history of disease or with a controlled disease

Exclusion criteria

Exclusion criteria: The patients with a history of psychiatric illness The patients with a history of peritonitis The patients with a history of hyperkalemia The patients with a history of renal and hepatic failure The patients with a history of malignant hyperthermia and pseudocholinesterase deficiency The patients with a history of addiction The patients with a history of benzodiazepines The patients with a history of burns

Design outcomes

Primary

MeasureTime frame
Agitation. Timepoint: From the moment of closing the gas until 10 minutes after estubation for once. Method of measurement: Emergency agitation of patients from the moment of gas closure until 10 minutes after extubation will be performed according to the criteria of Ricker Sedation Agitation Scale.;Myalgia. Timepoint: Myalgia pain scores will be recorded 1, 4, 8 and 24 hours after surgery. Method of measurement: Examination by a Physician.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Saeid Amniati

Iran University of Medical Sciences

amniati.s@iums.ac.ir+98 21 8670 1000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026