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Comparison of the effect of oral calcium Hydroxy-Apatite and calcium carbonate on prognosis of distal radius fracture surgery

Triple blind evaluation of the efficacy of oral calcium Hydroxy-apatite on post-operative pain, grip and bone mineral density after distal radius fracture surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210712051854N2
Enrollment
150
Registered
2022-04-16
Start date
2022-03-21
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

distal radius fracture. Fracture of lower end of radius

Interventions

Intervention 1: intervention group: In addition to follow up protocol (referring to clinic 1,3,6,12 weeks after surgery) and exercises to maintain range of motion of hand joints ,recieves oral Calcium

Sponsors

Daroo Salamat Pharmed
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients over 45 years of age with distal radius fracture referring to Shariati Hospital

Exclusion criteria

Exclusion criteria: Patients received treatment of osteoporosis including Bisphosphonate,calcium,vitamin D and Hormone therapy prior to the surgery Patients not being candidate for surgery due to specific medical condition with ASA score=3 or above Patients with mental disorders who may not adhere to the study

Design outcomes

Primary

MeasureTime frame
Bone mineral density. Timepoint: Immediately after surgery, 3 months after surgery,6 months after surgery. Method of measurement: dual-energy x-ray absorptiometry scan.;Pain rate. Timepoint: Immediately after surgery, 3 months after surgery,6 months after surgey. Method of measurement: Visual Analog Scale Questionnaire.;Union of fracture. Timepoint: monthly. Method of measurement: Radiography.

Secondary

MeasureTime frame
Grip Force. Timepoint: After surgery, ,3 months after surgery,6 months after surgery. Method of measurement: Measuring with Grip force meter.;Possible side effects of the drug. Timepoint: 3 months after surgery- 6 months after surgery. Method of measurement: Patient's Record and History.;Possible surgical complications. Timepoint: 3 months after surgery- 6 months after surgery. Method of measurement: Patient's Record and History.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Negar Mosavi Hasab

Daroo Salamat Pharmed

Negar.moosavi@daroosf.com+98 21 8819 2741

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026